Profhilo® H+L

• In the pack:

1 x 2ml syringe

• Benefits of Profhilo:

Improvement in tissue quality
Skin remodelling
Treatment of skin laxity
Restore skin firmness

• How long does the result last for?

Results are instant from the first treatment.
In general, results will last from 6 to 9 months and even up to one year depending on individual skin type factors, such as age, and lifestyle.

This product is from the European Community (EC)

• WHAT IS PROFHILO?

Profhilo is the first stabilized injectable product without BDDE based on hyaluronic acid (HA) for the treatment of skin laxity. It is used to obtain a tightening effect and a remodeling of the tissues, without effect of volume With one of the highest concentrations of HA on the market (64mg / 2ml), it does not only stimulate and hydrate the skin, but also reshapes aging and sagging tissue. Profhilo gives excellent results as a treatment alone or in combination with other cosmetic treatments currently on offer.

• TECHNICAL BAP:

To maximize diffusion in the malar and sub-malar areas:

- The BAPs were specifically chosen in the anatomically respective areas.
- The phenomenon of dilution of the product itself
- 5 injections per side
- Reduced pain (slow injection)
- Reduced possibility of bruising or bruising
- Reduction in the number of treatment sessions
- Better patient compliance

• HOW DOES PROFHILO® WORK?

As a stabilized product, Profhilo® stays in the skin for approximately 28 days. During this period, the stimulation of 4 different types of collagen and elastin takes place by the slow release of HA. This stimulation results in a significant improvement of the tissues. Therefore, we cannot say that Profhilo® is a skin booster as it also has a significant tightening / lifting effect on the tissues.

• UNIQUE PRODUCT

Profhilo has many features that make it unique compared to anything available on the market today. It does not contain BDDE. It is thermally crosslinked and generates stabilized hybrid cooperative complexes of H-HA and L-HA. Despite its high HA content, it has a low inflammatory profile, associated with pro-healing properties confirmed by clinical studies. To fully understand this new concept of anti-aging medicine, we must first look at the technology

• HOW IS PROFHILO STABILIZED?

Profhilo is developed using patented technology that produces cooperative hybrid complexes between high molecular weight HA and low molecular weight HA, without the use of chemical crosslinking compounds. These complexes increase the stability of HA to enzymatic and mechanical degradation.

• NAHYCO TECHNOLOGY

Profhilo is not a dermal filler or a biorevitalizer - Profhilo has opened a new category of injectable - bioremodeling. Thermal crosslinking alters the character and behavior of HA, resulting in the formation of cooperative hybrid complexes which modulate tissues. This is also the explanation of the different biological behavior compared to H-HA and L-HA alone. One of the main advantages is longevity. The cooperative hybrid complexes have been shown to be very stable to digestion by natural hyaluronidase (BTH) compared to H-HA, widely used in biorevitalization products, or to L-HA alone, hence the sustained release. and the double action of the two HA components. This double action is ideal for reshaping the laxity of the skin.

• BENEFITS

In Profhilo, L-HA is released slowly from hybrid HA complexes and therefore does not trigger the first inflammatory cytokines, making it very biocompatible. It also increases the comfort of the patient during and after the treatment and moisturizes the skin, especially the epidermis - the Hydro effect. The H-HA contained in Profhilo provides a stable HA architecture in the dermis. This gives a volumetric effect - the Lift effect. Another advantage of the stable cooperative hybrid complex over H-HA and L-HA is the increased expression levels of type I and type III collagen in fibroblasts and type IV and VII collagen. in keratinocytes. The result is an improvement in the quality and hydration of the skin, both in the dermis and in the epidermis. There is also an increase in the production of endogenous HA and elastin, which gives the skin a more youthful appearance.

• THE HIGHEST CONCENTRATION ON THE MARKET

Profhilo contains 32 mg of low molecular weight HA (80-100Kda) and 32 mg of high molecular weight HA (1100-1400Kda). This results in one of the highest concentrations of HA on the market - 64 mg of HA in a 2 ml pre-filled syringe. It is remarkable that this product can still be extruded with a 29g needle.